The United States confirmed 187,000 new coronavirus infections on Thursday — the highest one-day total of any nation since the start of the pandemic. More than 2,000 people died across the U.S. Thursday, the highest one-day death toll since May. Disease modelers at the University of Washington School of Medicine now predict over 470,000 U.S. coronavirus deaths by March 1 — unless face masks are widely adopted, something they say would save 65,000 lives.

The Centers for Disease Control and Prevention is calling on Americans to avoid travel over the Thanksgiving holiday, warning family get-togethers could lead to a spike in new infections and deaths.