The Centers for Disease Control and Prevention reports the United States saw more than 100,000 drug overdose deaths over a 12-month period ending in April, a nearly 30% increase over the previous year. It’s the first time annual U.S. overdose deaths reached six figures. Advocates say that isolation and stress brought on by the pandemic led to higher rates of drug abuse. Opioids, including the powerful drug fentanyl, accounted for about three-quarters of all overdose deaths.